Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Eric John Snijder0
Terrence William James0
Puck Bertyne van Kasteren0
Brian Leonard Mark0
Marjolein Kikkert0
Date of Patent
October 4, 2016
Patent Application Number
14035415
Date Filed
September 24, 2013
Patent Primary Examiner
Patent abstract
The present invention relates to replication-competent Arteriviruses having a decreased DUB/deISGylating activity due to a mutation in the PLP2 domain of the non-structural protein nsp2, to their use as a medicament, their use as a vaccine and in prophylaxis, to vaccines comprising such Arteriviruses and to Arteriviral PLP2-ubiquitin complexes.
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