Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hsiu-Mei Hsieh0
Ching-Fa Yao0
Guey-Jen Lee-Chen0
Date of Patent
July 19, 2016
0Patent Application Number
142823660
Date Filed
May 20, 2014
0Patent Primary Examiner
Patent abstract
A method for treating an abnormal polyglutamine-mediated disease is disclosed, wherein indole and an indole-based compound contained in a pharmaceutical composition used in the method of the present invention can reduce the polyglutamine aggregation through decreasing reactive oxygen species production and increasing the activity of chaperone and autophagy.
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