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US Patent 9365827 Cardiomyocyte production

Patent 9365827 was granted and assigned to Cellular Dynamics International on June, 2016 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Cellular Dynamics International
Cellular Dynamics International
Current Assignee
Cellular Dynamics International
Cellular Dynamics International
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9365827
Patent Inventor Names
Nathaniel Beardsley0
Wen Bo Wang0
Steven Kattman0
Casey Stankewicz0
Matt Riley0
Peter Fuhrken0
Date of Patent
June 14, 2016
Patent Application Number
13794654
Date Filed
March 11, 2013
Patent Primary Examiner
‌
Shin-Lin Chen
Patent abstract

Methods and composition for the production of cardiomyocytes from differentiation of pluripotent stem cells are provided. For example, in certain aspects methods including differentiating pluripotent stem cells in a large volume of suspension culture in the presence of ROCK inhibitors are described. In further aspects, methods for differentiation of stem cells into cardiomyocytes that overcome variability between different stem cell clones and different batch of culture medium are provided.

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