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US Patent 9297009 UNA oligomers targeting micro-RNA for therapeutics

Patent 9297009 was granted and assigned to Arcturus Therapeutics on March, 2016 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Arcturus Therapeutics
Arcturus Therapeutics
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Current Assignee
Arcturus Therapeutics
Arcturus Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
92970090
Patent Inventor Names
Jesper Wengel0
Date of Patent
March 29, 2016
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Patent Application Number
147030160
Date Filed
May 4, 2015
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Patent Citations Received
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US Patent 12083224 Lipid particles for nucleic acid delivery
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Patent Primary Examiner
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J. E. Angell
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Patent abstract

This invention provides UNA oligomers for therapeutics that can be used to target micro-RNAs. The UNA oligomers can be composed of one or more 2′-3′-seco-nucleomonomers and one or more natural or non-natural nucleotide monomers, and can be a single stranded oligomer. Embodiments include UNA oligomers with phosphorothioate or boranophosphate intermonomer linkages. The UNA oligomers can be used to target micro-RNAs to reduce micro-RNA activity.

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