Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Simon D. Edwards0
Basil Hartzoulakis0
David Madge0
Derek Edward John0
Fiona Chan0
Lindsay Brown0
Richard Blunt0
Date of Patent
March 22, 2016
0Patent Application Number
143587220
Date Filed
November 15, 2012
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides compounds of formula (I): (Formula (I); wherein A, R1, R2, R3I, V, X, and Z are defined herein, which are potassium channel inhibitors. The invention further provides pharmaceutical compositions comprising the compounds of formula (I) and their use in therapy, in particular in treatment of diseases or conditions that are mediated by Kir3.1 and/or Kir3.4 or any heteromultimers thereof, or that require inhibition of Kir3.1 and/or Kir3.4 or any heteromultimers thereof.
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