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US Patent 9266857 Bicyclic AZA compounds as muscarinic M1 receptor agonists

Patent 9266857 was granted and assigned to Heptares Therapeutics on February, 2016 by the United States Patent and Trademark Office.

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Is a

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Patent attributes

Patent Applicant

Heptares Therapeutics

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Current Assignee

Heptares Therapeutics

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Giles Albert Brown0

Julie Elaine Cansfield0

Mark Pickworth0

Miles Stuart Congreve0

Benjamin Gerald Tehan0

Date of Patent

February 23, 2016

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Patent Application Number

144289270

Date Filed

September 18, 2013

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Patent Citations Received

US Patent 12024499 Muscarinic agonists

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US Patent 11773090 Pharmaceutical compounds

US Patent 11834407 Substituted cyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists

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US Patent 11945801 Bicyclic aza compounds as muscarinic M

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Patent Primary Examiner

Niloofar Rahmani

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Patent abstract

This invention relates to compounds (Formula (1)) that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where R1-R5, X1, X2 and p are as defined herein.

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