Is a
Patent attributes
Patent Applicant
0
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael A. Jarvis0
Jay A. Nelson0
Klaus Frueh0
Louis Picker0
Scott G. Hansen0
Date of Patent
February 2, 2016
0Patent Application Number
136942800
Date Filed
November 14, 2012
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to recombinant rhesus cytomegalovirus (RhCMV) and human cytomegalovirus (HCMV) vectors encoding heterologous antigens, such as pathogen-specific antigens or tumor antigens, which may be used, for example, for the treatment or prevention of infectious disease or cancer. The recombinant RhCMV or HCMV vectors elicit and maintain high level cellular immune responses specific for the heterologous antigen while including deletions in one or more genes essential or augmenting for CMV replication, dissemination or spread.
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