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US Patent 9187465 Oxazole tyrosine kinase inhibitors

Patent 9187465 was granted and assigned to Sareum Limited on November, 2015 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Patent Applicant
Sareum Limited
Sareum Limited
Current Assignee
Sareum Limited
Sareum Limited
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9187465
Date of Patent
November 17, 2015
Patent Application Number
14529902
Date Filed
October 31, 2014
Patent Citations Received
‌
US Patent 11673870 Pharmaceutical compounds
0
Patent Primary Examiner
‌
Alicia L Otton
Patent abstract

The invention provides a compound which is an amide of the formula (1), or a salt, solvate, N-oxide or tautomer thereof; wherein: a is 0 or 1; b is 0 or 1: provided that the sum of a and b is 0 or 1; T is O or NH Ar1 is a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S, and being optionally substituted by one or more substituents R1; Ar2 Js a monocyclic or bicyclic 5- to 10-membered aryl or heteroaryl group containing up to 4 heteroatoms selected from O, N and S and being optionally substituted by one or more substituents R2; and R1 and R2 are as defined in the claims. The compounds are inhibitors of kinases and in particular FLT3, FLT4 and Aurora kinases.

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