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US Patent 9150639 Antibody and antibody fragment introduced new modification sites

Patent 9150639 was granted and assigned to Kyowa Hakko Kirin on October, 2015 by the United States Patent and Trademark Office.

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Current Assignee
Kyowa Hakko Kirin
Kyowa Hakko Kirin
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
91506390
Date of Patent
October 6, 2015
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Patent Application Number
130729240
Date Filed
March 28, 2011
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Patent Citations Received
‌
US Patent 11833222 CL and/or CH1 mutated antibodies for drug conjugation
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Patent Primary Examiner
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Phuong Huynh
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Patent abstract

The present invention relates to an antibody or antibody fragment comprising novel Cys residue, to which a hydrophilic macromolecular group or amphipathic macromolecular group can be bound at a high efficiency. In addition, the present invention relates to a monoclonal antibody modified product or an antibody fragment modified product in which cysteine residue is chemically modified.

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