A dynamically-changeable abdominal simulator system comprises a patient manikin having an abdominal cavity covered by a sheet of synthetic skin, a grid array of inflatable cells emplaced within the abdominal cavity covering respectively distinct areas of pressurization of the abdominal cavity and supplied with pressurized medium under separate and independent inflation control in order to simulate a wide range of abdominal ailments and/or conditional expressions thereof. In a preferred embodiment, the inflation cells of the grid array are each made of semi-rigid material for maintaining a fixed cell shape and contain an inflation balloon for pressurizing cell turgidity.