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US Patent 9096703 Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions

Patent 9096703 was granted and assigned to Semprus BioSciences on August, 2015 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee
Semprus BioSciences
Semprus BioSciences
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
90967030
Date of Patent
August 4, 2015
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Patent Application Number
131566770
Date Filed
June 9, 2011
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Patent Citations Received
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US Patent 12076545 Intravascular blood pumps and methods of use and manufacture
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US Patent 12121713 Catheter blood pumps and collapsible blood conduits
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US Patent 11654275 Intravascular blood pumps with struts and methods of use and manufacture
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Patent Primary Examiner
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Aaron Austin
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Patent abstract

A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm2 in a fibrinogen binding assay in which the modified surface is incubated for 60 minutes at 37° C. in 70 μg/mL fibrinogen derived from human plasma containing 1.4 μg/mL I-125 radiolabeled fibrinogen.

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