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US Patent 9057737 Immunoassay for thrombin detection

Patent 9057737 was granted and assigned to Omrix Biopharmaceuticals on June, 2015 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
Omrix Biopharmaceuticals
Omrix Biopharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
90577370
Patent Inventor Names
Roni Mintz0
Israel Nur0
Nadav Orr0
Date of Patent
June 16, 2015
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Patent Application Number
133072520
Date Filed
November 30, 2011
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Patent Primary Examiner
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Gail R Gabel
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Patent abstract

The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.

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