Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Theresa L. Murphy0
Jianfei Yang0
John R. Sedy0
Kenneth M. Murphy0
Michelle A. Hurchla Pyles0
Norihiko Watanabe0
Date of Patent
June 2, 2015
0Patent Application Number
133416110
Date Filed
December 30, 2011
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides a novel lymphocyte inhibitory receptor termed BTLA which is expressed on both T and B cells, and identifies HVEM as interacting with BTLA. Methods and compositions for modulating BTLA-mediated signaling and interfering with the interaction of BTLA and HVEM for therapeutic, diagnostic and research purposes are also provided.
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