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US Patent 9044495 Nucleic acid ligands to LL37

Patent 9044495 was granted and assigned to Biotex, Inc. on June, 2015 by the United States Patent and Trademark Office.

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Current Assignee
‌
Biotex, Inc.
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
9044495
Patent Inventor Names
George W. Jackson0
Date of Patent
June 2, 2015
Patent Application Number
13296163
Date Filed
November 14, 2011
Patent Primary Examiner
Janet Epps-Smith
Janet Epps-Smith
Patent abstract

The present invention is directed to nucleic acid ligands to LL37, methods for producing said nucleic acid ligands, and methods for utilizing said nucleic acid ligands. In one exemplary embodiment, for example, this invention relates to nucleic acid ligands exhibiting high specific binding affinity to LL37 peptides, precursors and/or portions thereof. Further, the nucleic acid ligands may bind competitively with native ligands of LL37 and may also inhibit and/or interfere with LL37 function, such as by binding to LL37.

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