Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
May 5, 2015
Patent Application Number
13127420
Date Filed
November 3, 2009
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides, among other things, chimeric DNA polymerases containing heterologous domains having sequences derived from at least two DNA polymerases that have at least one distinct functional characteristics (e.g., elongation rate, processivity, error rate or fidelity, salt tolerance or resistance) and methods of making and using the same. In some embodiments, the present invention can combine desired functional characteristics (e.g., high processivity; high elongation rate; thermostability; resistance to salt, PCR additives (e.g., PCR enhancers) and other impurities; and high fidelity) of different DNA polymerases in a chimeric polymerase.
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