Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yacov Ron0
Joseph P. Dougherty0
Sofiya Micheva-Viteva0
Stuart W. Peltz0
Annmarie Pacchia0
Date of Patent
April 28, 2015
0Patent Application Number
135512570
Date Filed
July 17, 2012
0Patent Primary Examiner
Patent abstract
Isolated, latently infected T cell lines are provided that can be utilized in high throughput screening to discover compounds capable of activating HIV-I. The T cell lines harbor a latent HIV-I derived vector pro virus, which upon activation expresses a marker for late viral gene expression due to the insertion of the marker gene in the position of HIV-I envelope.
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