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US Patent 9012421 Bicyclic cyclohexose nucleic acid analogs

Patent 9012421 was granted and assigned to Ionis Pharmaceuticals on April, 2015 by the United States Patent and Trademark Office.

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Patent abstract

The present invention provides bicyclic cyclohexose nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. These bicyclic nucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.

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