A system includes a climate-controlled inventory holder, a mobile drive unit, and a management module. The climate-controlled inventory holder is configured to control a climate of one or more inventory items stored by the inventory holder. The mobile drive unit is operable to transport the climate-controlled inventory holder from a first location to a second location based at least in part upon one or more instructions received from a management module. The management module is operable to receive an order for an inventory item, determine that the inventory holder stores the inventory item, and instruct the mobile drive unit to transport the climate-controlled inventory holder from the first location to the second location.