Heat transfer systems, methods and compositions which utilize a heat transfer fluid comprising: (a) from about 30% to about 65% by weight of HFC-134a; (b) from about 0% to about 70% by weight of HFO1234ze; and (c) from about 0% to about 70% by weight of HFO-1234yf, provided that the amount of HFO-1234ze and HFO-1234yf in the composition together is at least about 35% by weight, with the weight percent being based on the total of the components (a)-(c) in the composition.