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US Patent 8962580 Chemical modifications of monomers and oligonucleotides with cycloaddition

Patent 8962580 was granted and assigned to Alnylam Pharmaceuticals on February, 2015 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Alnylam Pharmaceuticals

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

89625800

Patent Inventor Names

David Butler0

Muthiah Manoharan0

Muthusamy Jayaraman0

Narayanannair K. Jayaprakash0

Rajendra K. Pandey0

Shigeo Matsuda0

Takeshi Yamada0

Chang Geng Peng0

...

Date of Patent

February 24, 2015

Patent Application Number

131203890

Date Filed

September 23, 2009

Patent Citations Received

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US Patent 12116382 Functionalized N-acetylgalactosamine analogs

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US Patent 11692001 Functionalized n-acetylgalactosamine analogs

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US Patent 11879125 GalNAc compositions for improving siRNA bioavailability

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US Patent 11884691 Functionalized n-acetylgalactosamine analogs

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US Patent 11993626 Functionalized N-acetylgalactosamine analogs

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US Patent 12005074 Extrahepatic delivery

Patent Primary Examiner

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James O. Wilson

Patent abstract

The invention features compounds of formula I or II:

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