Is a
Patent attributes
Current Assignee
0
Patent Jurisdiction
Patent Number
Patent Inventor Names
Duncan James Cochrane0
Jamie Iain Campbell0
Maria Anastasia Teresa Groves0
Simon Charles Cruwys0
David Christopher Lowe0
Donna Kirsty Finch0
Date of Patent
June 3, 2014
0Patent Application Number
136183660
Date Filed
September 14, 2012
0Patent Citations Received
Patent Primary Examiner
Patent abstract
This invention relates to binding members, especially antibody molecules, specific for interleukin 1 receptor 1 (IL-1R1). For example, isolated binding members specific for IL-1R1 which competes with IL-1 and IL-1Ra for binding to IL-1R1 and binds Il-1R1 with a KD of 10 pM or less when measured by Kinexa™. The binding members are useful for, inter alia, treatment of disorders mediated by IL-1R1 including rheumatoid arthritis, asthma and chronic obstructive pulmonary disease (COPD).
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