US Patent 8729239 Antibodies against fatty acid synthase

Patent 8729239 was granted and assigned to Nuclea Biotechnologies on May, 2014 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Nuclea Biotechnologies

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

87292390

Patent Inventor Names

Patrick J. Muraca0

Date of Patent

May 20, 2014

Patent Application Number

132586660

Date Filed

April 9, 2010

Patent Primary Examiner

‌

Sharon Wen

Patent abstract

The present invention relates to antibodies that immunospecifically bind to FAS and certain FAS related proteins. The invention encompasses human and humanized forms of the antibodies and their use in treating cancers and other proliferative disorders. The invention also relates to FAS-derived peptides useful for preparing the antibodies. Methods and compositions for detecting, diagnosing, treating or ameliorating a disease or disorder, especially cancer and other proliferative disorders using the present antibodies also are disclosed.