US Patent 8691531 Anti-CD79B antibodies and immunoconjugates and methods of use
Patent 8691531 was granted and assigned to Genentech on April, 2014 by the United States Patent and Trademark Office.
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The present invention is directed to compositions of matter comprising nucleic acids encoding a polypeptide comprising the amino acid sequence of SEQ ID NO: 207 or 208, encoding an anti-CD79b antibody comprising the heavy chain variable domain sequence of SEQ ID NO: 207 and the light chain variable domain sequence of SEQ ID NO: 208, or encoding an anti-CD79b antibody having : (i) a variable light chain comprising a HVR-L1 having the sequence of SEQ ID NO: 194, a HVR-L2 having the sequence of SEQ ID NO: 195, and a HVR-L3 having the sequence of SEQ ID NO: 196 and (ii) a variable light chain comprising a HVR-H1 having the sequence of SEQ ID NO: 202, a HVR-H2 having the sequence of SEQ ID NO: 203, and a HVR-H3 having the sequence of SEQ ID NO: 204, and vectors and host cells thereof.
US Patent 08691531 Anti-CD79B antibodies and immunoconjugates and methods of use US Patent 8691531 Anti-CD79B antibodies and immunoconjugates and methods of use
US Patent 08691531 Anti-CD79B antibodies and immunoconjugates and methods of use
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