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US Patent 8685691 Method for producing aminopeptidase

Patent 8685691 was granted and assigned to JCR Pharmaceuticals on April, 2014 by the United States Patent and Trademark Office.

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Patent
Patent

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Current Assignee
JCR Pharmaceuticals
JCR Pharmaceuticals
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8685691
Patent Inventor Names
Hiroyuki Sonoda0
Katsuya Daimon0
Atsushi Sugimura0
Date of Patent
April 1, 2014
Patent Application Number
12740146
Date Filed
October 25, 2008
Patent Primary Examiner
‌
Iqbal H Chowdhury
Patent abstract

Disclosed is an efficient method for production of aminopeptidase. The method comprises either transforming host bacteria with an aminopeptidase gene and with a neutral protease gene, or transforming some part of host bacteria with an aminopeptidase gene while transforming the other part of the host bacteria with a neutral protease gene, culturing in a medium the hose bacteria transformed with the aminopeptidase gene and with the neutral protease gene, or culturing a mixture of the host bacteria transformed with the aminopeptidase gene and the host bacteria transformed with the neutral protease gene, to let both the aminopeptidase and the neutral protease be expressed, and collecting the aminopeptidase thus produced from the culture mixture.

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