Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Allen J. Ebens, Jr.0
Frederic S. Jacobson0
Mark X. Sliwkowski0
Paul Polakis0
Ralph H. Schwall0
Susan D. Spencer0
Date of Patent
February 18, 2014
Patent Application Number
12052938
Date Filed
March 21, 2008
Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates to antibody-drug conjugate compounds of Formula I:Ab-(L-D)p Iwhere one or more maytansinoid drug moieties (D) are covalently linked by L to an antibody (Ab) which binds to an ErbB receptor, or which binds to one or more tumor-associated antigens or cell-surface receptors. These compounds may be used in methods of diagnosis or treatment of cancer, and other diseases and disorders.
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