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US Patent 8623364 Antigenic GM-CSF peptides and antibodies to GM-CSF

Patent 8623364 was granted and assigned to Morphotek, Inc. on January, 2014 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors

Is a

Patent

Patent attributes

Current Assignee

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Morphotek, Inc.

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

86233640

Patent Inventor Names

Wolfgang Ebel0

Nicholas C. Nicolaides0

Philip M. Sass0

Qimin Chao0

Eric Routhier0

Jian Li0

Luigi Grasso0

Date of Patent

January 7, 2014

Patent Application Number

136591650

Date Filed

October 24, 2012

Patent Primary Examiner

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Xiaozhen Xie

Patent abstract

Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, and methods of generating the hybridoma lines are provided. Target antigens and epitopes are also provided. The antibodies may be used in therapeutic methods, for example in the treatment of cancer, infectious disease, or autoimmune disease.