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US Patent 8486937 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and use thereof

Patent 8486937 was granted and assigned to Memory Pharmaceuticals on July, 2013 by the United States Patent and Trademark Office.

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Current Assignee
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Memory Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
84869370
Patent Inventor Names
Carla Maria Gauss0
Richard A. Schumacher0
Jianguo Ma0
Wenge Xie0
Truc Minh Nguyen0
Ashok Tehim0
Brian Herbert0
Date of Patent
July 16, 2013
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Patent Application Number
131653700
Date Filed
June 21, 2011
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Patent Primary Examiner
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Niloofar Rahmani
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Patent abstract

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

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