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US Patent 8478412 Method of improving sleep disordered breathing

Patent 8478412 was granted and assigned to Synapse Biomedical on July, 2013 by the United States Patent and Trademark Office.

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Current Assignee
Synapse Biomedical
Synapse Biomedical
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8478412
Patent Inventor Names
Anthony R. Ignagni6
Raymond P. Onders6
Date of Patent
July 2, 2013
Patent Application Number
12261979
Date Filed
October 30, 2008
Patent Citations Received
‌
US Patent 12070601 Stimulation system for exercising diaphragm and method of operation thereof
1
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US Patent 11707619 Apparatus and methods for assisted breathing by transvascular nerve stimulation
2
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US Patent 11771900 Circuitry for medical stimulation systems
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US Patent 11883658 Devices and methods for prevention, moderation, and/or treatment of cognitive injury
3
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US Patent 11890462 Stimulation systems and related user interfaces
4
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US Patent 11944810 Systems and methods for trans-esophageal sympathetic ganglion recruitment
5
Patent Primary Examiner
‌
Carl H Layno
Patent abstract

A diaphragm pacing stimulatory method and a system to implement the method are provided to improve respiratory function and the quality of sleep in patients whose sleep is compromised by poor respiration. The diaphragm pacing method includes adaptations that make it particularly compatible with the onset of sleep and sustaining sleep. Embodiments of the method are operated independently of breathing effort the patient may make during sleep. Patients for whom the invention is appropriate include those with a neuromuscular disease, such as amyotrophic lateral sclerosis (ALS). System elements include an external electrical stimulator coupled to one or more implanted electrodes that stimulate diaphragm contraction. The system and method provide for a pacing of the diaphragm, improved breathing, and improved sleep. Features of improved sleep include longer sleep time, an increased amount of REM sleep, and fewer episodes of wakefulness and restlessness.

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