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US Patent 8466288 Isoindolinone inhibitors of phosphatidylinositol 3-kinase

Patent 8466288 was granted and assigned to Vertex Pharmaceuticals on June, 2013 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

Vertex Pharmaceuticals

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Yusheng Liao0

Albert Charles Pierce0

Alex Aronov0

Anne-Laure Grillot0

Arnaud Le Tiran0

David Messersmith0

Elaine B. Krueger0

Hardwin O'Dowd0

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Date of Patent

June 18, 2013

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Patent Application Number

133498680

Date Filed

January 13, 2012

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Patent Citations Received

US Patent 12134620 Heterocyclic spiro compounds and methods of use thereof for the treatment of cancer

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US Patent 11878985 Substituted quinazolines as inhibitors of KRAS G12C

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Patent Primary Examiner

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Patent abstract

The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

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