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US Patent 8420363 Impedance based devices and methods for use in assays

Patent 8420363 was granted and assigned to ACEA Biosciences on April, 2013 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
ACEA Biosciences
ACEA Biosciences
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
84203630
Patent Inventor Names
Xiao Xu0
Xiaobo Wang0
Date of Patent
April 16, 2013
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Patent Application Number
123255300
Date Filed
December 1, 2008
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Patent Citations Received
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US Patent 12066428 Cell-substrate impedance monitoring of cancer cells
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US Patent 11746328 Methods and systems for functional maturation of iPSC and ESC derived cardiomyocytes
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US Patent 11835481 Physical vapor deposited biosensor components
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US Patent 11881549 Physical vapor deposited electrode for electrochemical sensors
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US Patent 11906508 Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution
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Patent Primary Examiner
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Nathan Bowers
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Patent abstract

A device for detecting cells and/or molecules on an electrode surface is disclosed. The device detects cells and/or molecules through measurement of impedance changes resulting from the cells and/or molecules. A disclosed embodiment of the device includes a substrate having two opposing ends along a longitudinal axis. A plurality of electrode arrays are positioned on the substrate. Each electrode array includes at least two electrodes, and each electrode is separated from at least one adjacent electrode in the electrode array by an expanse of non-conductive material. The electrode has a width at its widest point of more than about 1.5 and less than about 10 times the width of the expanse of non-conductive material. The device also includes electrically conductive traces extending substantially longitudinally to one of the two opposing ends of the substrate without intersecting another trace. Each trace is in electrical communication with at least one of the electrode arrays.

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