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US Patent 8389541 Inhibitors of protein tyrosine kinase activity

Patent 8389541 was granted and assigned to MethylGene on March, 2013 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
‌
MethylGene
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8389541
Patent Inventor Names
Stephen William Claridge0
Michael Mannion0
Oscar Mario Saavedra0
Stephane Raeppel0
Arkadii Vaisburg0
Frederic Gaudette0
Lijie Zhan0
Ljubomir Isakovic0
Date of Patent
March 5, 2013
Patent Application Number
13341604
Date Filed
December 30, 2011
Patent Primary Examiner
‌
Nizal Chandrakumar
Patent abstract

This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling and HGF receptor signaling. More particularly, the invention relates to compounds, compositions and methods for the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.

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