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US Patent 8377476 Butenafine hydrochloride-containing aqueous patch

Patent 8377476 was granted and assigned to Teikoku Seiyaku on February, 2013 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee
Teikoku Seiyaku
Teikoku Seiyaku
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
83774760
Patent Inventor Names
Yukiko Inamoto0
Kayo Tanigawa0
Takashi Kamakura0
Takefumi Hoshikawa0
Date of Patent
February 19, 2013
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Patent Application Number
129368150
Date Filed
March 24, 2009
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Patent Primary Examiner
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Robert A Wax
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Patent abstract

Disclosed is a water-based adhesive skin patch which has excellent storage stability, can achieve excellent accumulation of butenafine hydrochloride contained therein on a patched area such as the skin and a nail, and has a high therapeutic effect. Specifically disclosed is a water-based adhesive skin patch containing butenafine hydrochloride, which is characterized by containing butenafine hydrochloride, glycol salicylate and propylene glycol in a water-containing gel ointment. Specifically, butenafine hydrochloride is dissolved in a mixed solution of glycol salicylate and propylene glycol, and the resulting solution is dispersed in a water-containing gel. Particularly, the mixing ratio of glycol salicylate to propylene glycol is 1:2 to 1:30.

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