Patent attributes
The application relates to long acting injectable (LAI) formulations for combating ectoparasites and endoparasites in mammals. In particular, this invention provides for a LAI formulation comprising a subcutaneously volatile solvent, a biologically acceptable polymer, a bioactive agents and optionally one or more anti-ectoparasitically or anti-endoparasitically acceptable additive or excipient. Surprisingly, the liquid long acting injectable formulations of the invention solve the problems associates with previous injectable formulations by having long term stability, being able to accommodate smaller needle diameters and achieving long acting effects in the control of pests in a mammal. The unique formulations of the invention also allow for combating ectoparasites and endoparasites which have become resistant to macrolide antibiotics.
