Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Judith Christina T. Van Deutekom0
Annemieke Aartsma-Rus0
Garrit-Jan Boudewijn Van Ommen0
Date of Patent
January 29, 2013
Patent Application Number
12300629
Date Filed
March 18, 2007
Patent Citations Received
0
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Patent Primary Examiner
Patent abstract
In the present invention means and method are provided for optimising exon-skipping using exon-internal AON. We show that skipping efficiencies are improved by targeting putative splicing regulatory sequences (ESEs) within an exon. Such double targeting may be particularly useful for exons with which efficient skipping was difficult to obtain prior to the invention.
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