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US Patent 8354109 Multimeric Fc receptor polypeptides

Patent 8354109 was granted and assigned to SuppreMol on January, 2013 by the United States Patent and Trademark Office.

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Current Assignee
‌
SuppreMol
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8354109
Date of Patent
January 15, 2013
Patent Application Number
11762664
Date Filed
June 13, 2007
Patent Primary Examiner
‌
Michael Szperka
Patent abstract

A soluble multimeric protein or polypeptide is disclosed that is able to inhibit interaction of leukocyte Fcγ receptors (FcγR) and immunoglobulin G (IgG). The protein or polypeptide comprises two or more linked Fc binding regions, at least one of which is derived from an FcγR type receptor and, particularly, FcγRIIa. Also described are polynucleotide molecules encoding the protein or polypeptide and the use thereof in methods of treating a subject for an immune-complex (IC)-mediated inflammatory disease.

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