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US Patent 8343545 Method of producing microparticles

Patent 8343545 was granted and assigned to University College London (UCL) on January, 2013 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors

Is a

Patent

Patent attributes

Current Assignee

University College London (UCL)

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

83435450

Patent Inventor Names

Sudax Shina Murdan0

Abdul Waseh Basit0

Richard Andrew Kendall0

Date of Patent

January 1, 2013

Patent Application Number

105973280

Date Filed

January 19, 2005

Patent Primary Examiner

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Frederick Krass

Patent abstract

A method of producing microparticles having a median diameter up to 100 μm and the microparticles so produced are described. The method includes the steps of providing a solvent having a bioactive dispersed or dissolved therein and a vehicle dissolved therein, carrying out an emulsification in a non-solvent phase to produce an emulsion containing the bioactive and the vehicle in a solvent phase, and evaporating the solvent to leave the microparticles, wherein a mixture of at least two surfactants is employed to stabilize the emulsion and wherein the mixture has a hydrophilic-lipophilic balance (HLB) of up to 8.