Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Katrin Spiegel0
Urs Baettig0
Glyn Hughes0
Kamlesh Jagdis Bala0
Lee Edwards0
Catherine Howsham0
Darren Mark Legrand0
Emma Budd0
Date of Patent
August 21, 2012
0Patent Application Number
130473190
Date Filed
March 14, 2011
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
The present invention provides pyridine and pyrazine derivatives which restore or enhance the function of mutant and/or wild type CFTR to treat cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia and keratoconjunctivitis sire, or constipation (IBS, IBD, opioid induced). Pharmaceutical compositions comprising such derivatives are also encompassed.
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