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US Patent 8242305 Process to prepare treprostinil, the active ingredient in remodulin

Patent 8242305 was granted and assigned to United Therapeutics on August, 2012 by the United States Patent and Trademark Office.

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Patent abstract

This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

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