Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
May 29, 2012
Patent Application Number
12961733
Date Filed
December 7, 2010
Patent Citations Received
Patent Primary Examiner
Patent abstract
Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have improved stability compared to wild-type mature human IL-12p40 polypeptides.
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