Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Brad Edmund Sleebs0
Jonathan Bayldon Baell0
Michael F. T. Koehler0
Wayne J. Fairbrother0
Guillaume Laurent Lessene0
John A. Flygare0
Date of Patent
May 1, 2012
0Patent Application Number
125138350
Date Filed
November 15, 2007
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates generally to small molecules that mimic the biological activity of certain peptides and proteins, to compositions containing them and to their use. In particular, the invention relates to compounds of the general formula (I) that mimic the biological activity of BH3-only proteins and are capable of binding to and neutralizing pro-survival Bcl-2 proteins:
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