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US Patent 8163756 Enzyme modulators and treatments

Patent 8163756 was granted and assigned to Deciphera Pharmaceuticals on April, 2012 by the United States Patent and Trademark Office.

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US Patent 12102620 Combination therapy for the treatment of mastocytosis

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US Patent 12071432 Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof

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US Patent 12064422 Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea

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US Patent 12059411 Methods of treating gastrointestinal stromal tumors

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US Patent 12059410 Methods of treating gastrointestinal stromal tumors

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US Patent 12023328 Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea

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US Patent 12023327 Methods of treating gastrointestinal stromal tumors

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US Patent 12023326 Methods of treating gastrointestinal stromal tumors

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US Patent 12023325 Methods of treating gastrointestinal stromal tumors

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US Patent 11986463 Combination therapy for the treatment of gastrointestinal stromal tumor

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US Patent 11969415 (methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea

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US Patent 11969414 Methods of treating gastrointestinal stromal tumors

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US Patent 11952370 Selective ligands for modulation of GIRK channels

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US Patent 11918564 Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea

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US Patent 11912668 GCN2 and perk kinase inhibitors and methods of use thereof

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US Patent 11911370 Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea

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US Patent 11903933 Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea

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US Patent 11850241 Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea

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US Patent 11850240 Compositions of 1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluoropheyl)-3-phenylurea

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Article (+491 characters)

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Patent abstract

Novel compounds and methods of using those compounds for the treatment of inflammatory conditions, hyperproliferative diseases, cancer, and diseases characterized by hyper-vascularization are provided. In a preferred embodiment, modulation of the activation state of p38 kinase protein, abl kinase protein, ber-abl kinase protein, braf kinase protein, VEGFR kinase protein, or PDGFR kinase protein comprises the step of contacting said kinase protein with the novel compounds.

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