US Patent 8153110 Environment-responding siRNA carrier using disulfide-cross-linked polymeric micelle
Patent 8153110 was granted and assigned to The University of Tokyo Edge Capital on April, 2012 by the United States Patent and Trademark Office.
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Patent abstract
Disclosed is a siRNA-encapsulating polymeric micelle complex (a polyion complex) having high monodispersibility and structural stability and excellent in the ability of transporting siRNA into a cell. Further disclosed are a nucleic acid delivery device, a nucleic acid delivery kit, a pharmaceutical composition, and a gene therapy agent, each of which uses the complex. The polyion complex is characterized by comprising: a block copolymer composed of a polyethylene glycol moiety and a polycation moiety having a thiol group as a side chain at the terminus; and siRNA.
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US Patent 08153110 Environment-responding siRNA carrier using disulfide-cross-linked polymeric micelle US Patent 8153110 Environment-responding siRNA carrier using disulfide-cross-linked polymeric micelle
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Patent Number
0815311000
Patent Number
815311000
Edits on 28 Apr, 2023
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Infobox
Is a
Current Assignee
Patent Jurisdiction
Patent Number
081531100
Date of Patent
April 10, 2012
0Patent Application Number
125154640
Date Filed
November 22, 2007
0Patent Primary Examiner
Edits on 23 Sep, 2022
Golden AI
Infobox
Is a
Current Assignee
Patent Jurisdiction
Patent Number
081531100
Date of Patent
April 10, 2012
0Patent Application Number
125154640
Date Filed
November 22, 2007
0Patent Primary Examiner
Edits on 14 Dec, 2021
Golden AI
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Infobox (+8 properties)
US Patent 08153110 Environment-responding siRNA carrier using disulfide-cross-linked polymeric micelle
Infobox
Is a
Current assignee
Patent jurisdiction
Patent number
08153110
Date of patent
April 10, 2012
Patent application number
12515464
Date Filed
November 22, 2007
Patent primary examiner
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