US Patent 8142784 Antibody-drug conjugates and methods
Patent 8142784 was granted and assigned to Genentech on March, 2012 by the United States Patent and Trademark Office.
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Patent abstract
The present invention relates to antibody-drug conjugate compounds of Formula I:Ab-(L-D)p Iwhere one or more maytansinoid drug moieties (D) are covalently linked by L to an antibody (Ab) which binds to an ErbB receptor, or which binds to one or more tumor-associated antigens or cell-surface receptors. These compounds may be used in methods of diagnosis or treatment of cancer, and other diseases and disorders.
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Patent Inventor Names
Allen J. Ebens, Jr.0
Frederic S. Jacobson0
Mark X. Sliwkowski0
Paul Polakis0
Ralph H. Schwall0
Susan D. Spencer0
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US Patent 08142784 Antibody-drug conjugates and methods US Patent 8142784 Antibody-drug conjugates and methods
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Patent Number
081427840
Patent Number
81427840
Edits on 27 Mar, 2023
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Is a
Current Assignee
Patent Jurisdiction
Patent Number
081427840
Date of Patent
March 27, 2012
0Patent Application Number
123267210
Date Filed
December 2, 2008
0Patent Primary Examiner
Edits on 14 Dec, 2021
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US Patent 08142784 Antibody-drug conjugates and methods
Infobox
Is a
Current assignee
Patent jurisdiction
Patent number
08142784
Date of patent
March 27, 2012
Patent application number
12326721
Date Filed
December 2, 2008
Patent primary examiner
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