An automobile detection and control gateway interface and a method thereof are provided. The automobile detection and control gateway interface is connected with a controller area network (CAN) formed by a body control module (BCM) and body devices, and pre-stores a plurality of device diagnostic commands and status diagnostic data, so that the BCM performs corresponding actions on specific body devices according to the device diagnostic commands and capture status feedback data transmitted over the CAN by the body devices, and outputs the status diagnostic data matching with the status feedback data for determining the operation status of the body devices or for the externally connected device to acquire. All the device diagnostic commands are transferred through the BCM to avoid interfering with the operation of the CAN and control the external device connected to the BCM, so as to ensure all the body devices are under control.