Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yingsheng Wang0
Regis Leung-Tuong0
Tim Fat Tam0
Yanqing Zhao0
Blaise N'Zemba0
Lily Yu0
Date of Patent
February 21, 2012
Patent Application Number
12515217
Date Filed
November 26, 2007
Patent Primary Examiner
Patent abstract
A process for making pure crystalline D-isoglutamyl-D-tryptophan is provided which includes the step of deprotecting essentially pure N-tert-butoxycarbonyl-D-isoglutamyl-D-tryptophan or its diester to yield essentially pure D-isoglutamyl-D-tryptophan. A process is also provided for the preparation of pure mono ammonium salt of D-isoglutamyl-D-tryptophan from essentially pure N-tert-butoxycarbonyl-D-isoglutamyl-D-tryptophan. D-isoglutamyl-D-tryptophan, ammonium salt (1:1) is a stable pharmaceutical solid.
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