Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ian Graham0
John George Dickson0
Linda Popplewell0
Date of Patent
December 27, 2011
0Patent Application Number
125566260
Date Filed
September 10, 2009
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
Molecules are provided for inducing or facilitating exon skipping in forming spliced mRNA products from pre-mRNA molecules in cells. The molecules may be provided directly as oligonucleotides or expression products of vectors that are administered to a subject. High rates of skipping can be achieved. High rates of skipping reduce the severity of a disease like Duchene Muscular Dystrophy so that the disease is more like Becker Muscular Dystrophy. This is a severe reduction in symptom severity and mortality.
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