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US Patent 8084462 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof

Patent 8084462 was granted and assigned to Targacept, Inc. on December, 2011 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to the pharmaceutical compositions incorporating compounds capable of affecting nicotinic acetylcholinergic receptors (nAChRs), for example, as modulators of specific nicotinic receptor subtypes (specifically, the α7 nAChR subtype). The present invention also relates to methods for treating a wide variety of conditions and disorders, particularly those associated with dysfunction of the central and autonomic nervous systems.

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