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US Patent 8048289 Parallel patch clamp system

Patent 8048289 was granted and assigned to Molecular Devices on November, 2011 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
Molecular Devices
Molecular Devices
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
8048289
Patent Inventor Names
Alan S. Finkel0
Date of Patent
November 1, 2011
Patent Application Number
11222576
Date Filed
September 9, 2005
Patent Citations Received
‌
US Patent 12085559 Replaceable ground electrode for electrophysiology, electrode rejuvenating apparatus, and related methods and systems
0
Patent Primary Examiner
‌
Kaj K. Olsen
Patent abstract

A system for high-throughput analysis of membranous samples having ion channels including at least one membranous sample, a multi-compartment structure including an extracellular chamber, an opposing intracellular chamber and a partition separating the extracellular and intracellular chambers, the partition having a plurality of apertures fluidly and electrically coupling the extracellular and intracellular chambers, wherein at least one of the apertures is sealed by the at least one membranous sample, and another of the apertures is unsealed, a electric source configured to apply a current between the extracellular and intracellular chambers, wherein a portion of the current travels through the unsealed aperture, and a current sensor configured to measure the current between the extracellular and intracellular chambers. A method of using the system is also disclosed.

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