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US Patent 8034623 Method for free radical initiated peptide sequencing

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Bong-Jin Moon0

Han-Bin Oh0

Min-Hee Lee0

Min-hyuck Kang0

Date of Patent

October 11, 2011

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Patent Application Number

125792890

Date Filed

October 14, 2009

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Patent Citations Received

US Patent 12065466 Methods and compositions for protein sequencing

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US Patent 11959105 Polymerizing enzymes for sequencing reactions

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US Patent 11959920 Methods and compositions for protein sequencing

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US Patent 11970729 Methods for nucleic acid sequencing

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US Patent 12000835 Methods and compositions for protein sequencing

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US Patent 12011716 Peristaltic pumping of fluids and associated methods, systems, and devices

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US Patent 12019076 Means and methods for single molecule peptide sequencing

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Patent Primary Examiner

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Patent abstract

The present invention relates to a free radical initiator and a method for peptide sequencing using the same. Compared with diazo or peroxy functionalized precursors, the precursors using the present compounds are chemically more robust and can generate radical species by homolytic cleavage upon thermal activation, enabling sequencing of a wider variety of peptides. In addition, the present invention makes it feasible to sequence peptides carrying disulfide bonds.

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