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US Patent 8013183 Alpha ketoamide compounds as cysteine protease inhibitors

Patent 8013183 was granted and assigned to Virobay on September, 2011 by the United States Patent and Trademark Office.

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Michael Graupe0

John O. Link0

Michael G. Roepel0

Date of Patent

September 6, 2011

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Patent Application Number

127112170

Date Filed

February 23, 2010

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Patent Primary Examiner

Shailendra Kumar

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Patent abstract

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

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